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Proteins ZNF198 and SUZ12 are down-regulated in Hepatitis B virus (HBV) X protein-mediated hepatocyte transformation and in HBV replication

Chronic Hepatitis B Virus (HBV) infection is a major etiologic factor in hepatocellular carcinoma (HCC) pathogenesis, involving effects of chronic liver inflammation and of the weakly oncogenic HBV X protein (pX). pX-mediated hepatocyte transformation requires Polo-like kinase1 (Plk1) activity, but...

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Detalhes bibliográficos
Main Authors: Wang, Wen-Horng, Studach, Leo L., Andrisani, Ourania M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079326/
https://ncbi.nlm.nih.gov/pubmed/21480320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24163
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