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A subset of Suz12/PRC2 target genes is activated during HBV replication and liver carcinogenesis associated with hepatitis B virus X protein

Chronic hepatitis B virus (HBV) infection is a major risk factor for developing liver cancer, and the HBV X protein (pX) has been implicated as a cofactor in hepatocyte transformation. We have shown that HBV replication as well as in vitro transformation by pX are associated with induction of the mi...

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Detalhes bibliográficos
Main Authors: Studach, Leo L., Menne, Stephan, Cairo, Stefano, Buendia, Marie Annick, Hullinger, Ronald L., Lefrançois, Lydie, Merle, Philippe, Andrisani, Ourania M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417088/
https://ncbi.nlm.nih.gov/pubmed/22505317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25781
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