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ERK-MAPK Drives Lamellipodia Protrusion by Activating the WAVE2 Regulatory Complex
Cell movement begins with a leading edge protrusion, which is stabilized by nascent adhesions and retracted by mature adhesions. The ERK-MAPK (extracellular signal regulated kinasemitogen-activated protein kinase) localizes to protrusions and adhesions, but how it regulates motility is not understoo...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078620/ https://ncbi.nlm.nih.gov/pubmed/21419341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.02.031 |
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