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ERK reinforces actin polymerization to power persistent edge protrusion during motility

Cells move through perpetual protrusion and retraction cycles at the leading edge. These cycles are coordinated with substrate adhesion and retraction of the cell rear. Here, we tracked spatial and temporal fluctuations in the molecular activities of individual moving cells to elucidate how extracel...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Mendoza, Michelle C., Vilela, Marco, Juarez, Jesus E., Blenis, John, Danuser, Gaudenz
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4830495/
https://ncbi.nlm.nih.gov/pubmed/25990957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa8859
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