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Modeling of Protrusion Phenotypes Driven by the Actin-Membrane Interaction

We propose a mathematical model for simulating the leading-edge dynamics of a migrating cell from the interplay among elastic properties, architecture of the actin cytoskeleton, and the mechanics of the membrane. Our approach is based on the description of the length and attachment dynamics of actin...

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Detalhes bibliográficos
Main Authors: Enculescu, Mihaela, Sabouri-Ghomi, Mohsen, Danuser, Gaudenz, Falcke, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856167/
https://ncbi.nlm.nih.gov/pubmed/20409477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4311
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