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S-Glutathionylation Reshapes Our Understanding of Endothelial Nitric Oxide Synthase Uncoupling and Nitric Oxide/Reactive Oxygen Species-Mediated Signaling
Oxidative stress has been shown to convert endothelial nitric oxide synthase (eNOS) from an NO-producing enzyme to an enzyme that generates superoxide, a process termed NOS uncoupling. This uncoupling of eNOS converts it to function as an NADPH oxidase with superoxide and hydrogen peroxide generatio...
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Päätekijät: | , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Mary Ann Liebert, Inc.
2011
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078498/ https://ncbi.nlm.nih.gov/pubmed/21261471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.3904 |
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