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S-Glutathionylation Reshapes Our Understanding of Endothelial Nitric Oxide Synthase Uncoupling and Nitric Oxide/Reactive Oxygen Species-Mediated Signaling

Oxidative stress has been shown to convert endothelial nitric oxide synthase (eNOS) from an NO-producing enzyme to an enzyme that generates superoxide, a process termed NOS uncoupling. This uncoupling of eNOS converts it to function as an NADPH oxidase with superoxide and hydrogen peroxide generatio...

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書誌詳細
主要な著者: Zweier, Jay L., Chen, Chun-An, Druhan, Lawrence J.
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078498/
https://ncbi.nlm.nih.gov/pubmed/21261471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.3904
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