Obesity and Hepatosteatosis in Mice with Enhanced Oxidative DNA Damage Processing in Mitochondria

Mitochondria play critical roles in oxidative phosphorylation and energy metabolism. Increasing evidence supports that mitochondrial DNA (mtDNA) damage and dysfunction play vital roles in the development of many mitochondria-related diseases, such as obesity, diabetes mellitus, infertility, neurodeg...

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Detalhes bibliográficos
Main Authors: Zhang, Haihong, Xie, Chenghui, Spencer, Horace J., Zuo, Chunlai, Higuchi, Masahiro, Ranganathan, Gouri, Kern, Philip A., Chou, Ming W., Huang, Qin, Szczesny, Bartosz, Mitra, Sankar, Watson, Amanda J., Margison, Geoffrey P., Fan, Chun-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078437/
https://ncbi.nlm.nih.gov/pubmed/21435453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.038
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