Obesity and Hepatosteatosis in Mice with Enhanced Oxidative DNA Damage Processing in Mitochondria

Mitochondria play critical roles in oxidative phosphorylation and energy metabolism. Increasing evidence supports that mitochondrial DNA (mtDNA) damage and dysfunction play vital roles in the development of many mitochondria-related diseases, such as obesity, diabetes mellitus, infertility, neurodeg...

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Autores principales: Zhang, Haihong, Xie, Chenghui, Spencer, Horace J., Zuo, Chunlai, Higuchi, Masahiro, Ranganathan, Gouri, Kern, Philip A., Chou, Ming W., Huang, Qin, Szczesny, Bartosz, Mitra, Sankar, Watson, Amanda J., Margison, Geoffrey P., Fan, Chun-Yang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2011
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078437/
https://ncbi.nlm.nih.gov/pubmed/21435453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.038
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