Obesity and Hepatosteatosis in Mice with Enhanced Oxidative DNA Damage Processing in Mitochondria

Mitochondria play critical roles in oxidative phosphorylation and energy metabolism. Increasing evidence supports that mitochondrial DNA (mtDNA) damage and dysfunction play vital roles in the development of many mitochondria-related diseases, such as obesity, diabetes mellitus, infertility, neurodeg...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Haihong, Xie, Chenghui, Spencer, Horace J., Zuo, Chunlai, Higuchi, Masahiro, Ranganathan, Gouri, Kern, Philip A., Chou, Ming W., Huang, Qin, Szczesny, Bartosz, Mitra, Sankar, Watson, Amanda J., Margison, Geoffrey P., Fan, Chun-Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2011
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078437/
https://ncbi.nlm.nih.gov/pubmed/21435453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.038
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