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Naproxen Interferes with the Assembly of Aβ Oligomers Implicated in Alzheimer's Disease

Experimental and epidemiological studies have shown that the nonsteroidal antiinflammatory drug naproxen may be useful in the treatment of Alzheimer's disease. To investigate the interactions of naproxen with Aβ dimers, which are the smallest cytotoxic aggregated Aβ peptide species, we use unit...

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Hlavní autoři: Kim, Seongwon, Chang, Wenling E., Kumar, Rashmi, Klimov, Dmitri K.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077692/
https://ncbi.nlm.nih.gov/pubmed/21504739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.044
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