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Synthesis and Biological Evaluation of Bivalent Ligands for the CB1 Receptor

Dimerization or oligomerization of many G protein-coupled receptors, including the CB1 receptor, is now widely accepted and may have significant implications towards medications development targeting these receptor complexes. A library of bivalent ligands composed of two identical CB1 antagonist pha...

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Bibliographic Details
Main Authors: Zhang, Yanan, Gilliam, Anne, Maitra, Rangan, Damaj, M. Imad, Tajuba, Julianne M., Seltzman, Herbert H., Thomas, Brian F.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076737/
https://ncbi.nlm.nih.gov/pubmed/20845959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm1006676
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