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NF-κB Signaling: Multiple angles to target OA

In the context of OA disease, NF-κB transcription factors can be triggered by a host of stress-related stimuli including pro-inflammatory cytokines, excessive mechanical stress and ECM degradation products. Activated NF-κB regulates the expression of many cytokines and chemokines, adhesion molecules...

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Bibliographic Details
Main Authors: Marcu, Kenneth B., Otero, Miguel, Olivotto, Eleonora, Borzi, Rosa Maria, Goldring, Mary B.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076145/
https://ncbi.nlm.nih.gov/pubmed/20199390
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