Identification of SR3335 (ML176): a Synthetic RORα Selective Inverse Agonist

Several nuclear receptors (NRs) are still characterized as orphan receptors since ligands have not yet been identified for these proteins. The retinoic acid receptor-related receptors (RORs) have no well-defined physiological ligands. Here, we describe the identification of a selective RORα syntheti...

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Hauptverfasser: Kumar, Naresh, Kojetin, Douglas J., Solt, Laura A., Kumar, K. Ganesh, Nuhant, Philippe, Duckett, Derek R., Cameron, Michael D., Butler, Andrew A., Roush, William R., Griffin, Patrick R., Burris, Thomas P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076127/
https://ncbi.nlm.nih.gov/pubmed/21090593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb1002762
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