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Exploration of Dimensions of Estrogen Potency: PARSING LIGAND BINDING AND COACTIVATOR BINDING AFFINITIES

The estrogen receptors, ERα and ERβ, are ligand-regulated transcription factors that control gene expression programs in target tissues. The molecular events underlying estrogen action involve minimally two steps, hormone binding to the ER ligand-binding domain followed by coactivator recruitment to...

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Autori principali: Jeyakumar, M., Carlson, Kathryn E., Gunther, Jillian R., Katzenellenbogen, John A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075970/
https://ncbi.nlm.nih.gov/pubmed/21321128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.205112
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