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The BRCA1-RAP80 Complex Regulates DNA Repair Mechanism Utilization by Restricting End Resection
The tumor suppressor protein BRCA1 is a constituent of several different protein complexes and is required for homology-directed repair (HDR) of DNA double strand breaks (DSBs). The most recently discovered BRCA1-RAP80 complex is recruited to ubiquitin structures on chromatin surrounding the break....
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075711/ https://ncbi.nlm.nih.gov/pubmed/21335604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.213728 |
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