Differential Regulation of JAMM Domain Deubiquitinating Enzyme Activity within the RAP80 Complex

BRCC36 is a JAMM (JAB1/MPN/Mov34 metalloenzyme) domain, lysine 63-ubiquitin (K63-Ub)-specific deubiquitinating enzyme (DUB) and a member of two protein complexes: the DNA damage-responsive BRCA1-RAP80 complex, and the cytoplasmic BRCC36 isopeptidase complex (BRISC). The presence of several identical...

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Bibliografiska uppgifter
Huvudupphovsmän: Patterson-Fortin, Jeffrey, Shao, Genze, Bretscher, Heidi, Messick, Troy E., Greenberg, Roger A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
DNA and Chromosomes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945588/
https://ncbi.nlm.nih.gov/pubmed/20656689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135319
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