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Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function
Germline mutations in two major susceptibility genes, BRCA1 and BRCA2, account for nearly 20% of familial breast cancers. A majority of the remaining genetic factors involved in heritable breast cancer susceptibility are, however, unknown. Recently, a new BRCA1-interacting protein, RAP80, was identi...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2009
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692655/ https://ncbi.nlm.nih.gov/pubmed/19305427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.33 |
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