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Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function
Germline mutations in two major susceptibility genes, BRCA1 and BRCA2, account for nearly 20% of familial breast cancers. A majority of the remaining genetic factors involved in heritable breast cancer susceptibility are, however, unknown. Recently, a new BRCA1-interacting protein, RAP80, was identi...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2692655/ https://ncbi.nlm.nih.gov/pubmed/19305427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.33 |
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