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Molecular structure of the halogenated anti-cancer drug iododoxorubicin complexed with d(TGTACA) and d(CGATCG).

4'-Deoxy-4'-iododoxorubicin, a halogenated anthracycline derivative, is an anticancer agent currently under Phase II clinical trials. In preclinical studies, it has demonstrated significantly reduced levels of cardiotoxicity compared to currently employed anthracyclines. It also has modified pharmac...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Berger, I, Su, L, Spitzner, J R, Kang, C, Burke, T G, Rich, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1995
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307408/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501474/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4488
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