Molecular structure of the halogenated anti-cancer drug iododoxorubicin complexed with d(TGTACA) and d(CGATCG).

4'-Deoxy-4'-iododoxorubicin, a halogenated anthracycline derivative, is an anticancer agent currently under Phase II clinical trials. In preclinical studies, it has demonstrated significantly reduced levels of cardiotoxicity compared to currently employed anthracyclines. It also has modified pharmac...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Berger, I, Su, L, Spitzner, J R, Kang, C, Burke, T G, Rich, A
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1995
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307408/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4488
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