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Ternary interactions of spermine with DNA: 4'-epiadriamycin and other DNA: anthracycline complexes.
The recently developed anthracycline 4'-epiadriamycin, an anti-cancer drug with improved activity, differs from adriamycin by inversion of the stereochemistry at the 4'-position. We have cocrystallized 4'-epiadriamycin with the DNA hexamer d(CGATCG) and solved the structure to 1.5 A r...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1990
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC332234/ https://ncbi.nlm.nih.gov/pubmed/2216725 |
| Tagit: |
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