Ternary interactions of spermine with DNA: 4'-epiadriamycin and other DNA: anthracycline complexes.
The recently developed anthracycline 4'-epiadriamycin, an anti-cancer drug with improved activity, differs from adriamycin by inversion of the stereochemistry at the 4'-position. We have cocrystallized 4'-epiadriamycin with the DNA hexamer d(CGATCG) and solved the structure to 1.5 A resolution using...
Kaydedildi:
| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
1990
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| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332234/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2216725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.18.5533 |
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