Molecular structure of the halogenated anti-cancer drug iododoxorubicin complexed with d(TGTACA) and d(CGATCG).

4'-Deoxy-4'-iododoxorubicin, a halogenated anthracycline derivative, is an anticancer agent currently under Phase II clinical trials. In preclinical studies, it has demonstrated significantly reduced levels of cardiotoxicity compared to currently employed anthracyclines. It also has modified pharmac...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Berger, I, Su, L, Spitzner, J R, Kang, C, Burke, T G, Rich, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1995
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307408/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4488
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