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Molecular structure of the halogenated anti-cancer drug iododoxorubicin complexed with d(TGTACA) and d(CGATCG).

4'-Deoxy-4'-iododoxorubicin, a halogenated anthracycline derivative, is an anticancer agent currently under Phase II clinical trials. In preclinical studies, it has demonstrated significantly reduced levels of cardiotoxicity compared to currently employed anthracyclines. It also has modified pharmac...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Principais autores: Berger, I, Su, L, Spitzner, J R, Kang, C, Burke, T G, Rich, A
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1995
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307408/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501474/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4488
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