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Molecular structure of the halogenated anti-cancer drug iododoxorubicin complexed with d(TGTACA) and d(CGATCG).

4'-Deoxy-4'-iododoxorubicin, a halogenated anthracycline derivative, is an anticancer agent currently under Phase II clinical trials. In preclinical studies, it has demonstrated significantly reduced levels of cardiotoxicity compared to currently employed anthracyclines. It also has modified pharmac...

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Publicado no:Nucleic Acids Res
Principais autores: Berger, I, Su, L, Spitzner, J R, Kang, C, Burke, T G, Rich, A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1995
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307408/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501474/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4488
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