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First total synthesis and antileishmanial activity of (Z)-16-methyl-11-heptadecenoic acid, a new marine fatty acid from the sponge Dragmaxia undata

The first total synthesis for the (Z)-16-methyl-11-heptadecenoic acid, a novel fatty acid from the sponge Dragmaxia undata, was accomplished in seven steps and in a 44% overall yield. The use of (trimethylsilyl)acetylene was key in the synthesis. Based on a previous developed strategy in our laborat...

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Bibliografski detalji
Glavni autori: Carballeira, Néstor M., Montano, Nashbly, Cintrón, Gabriel A., Márquez, Carmary, Rubio, Celia Fernández, Prada, Christopher Fernández, Balaña-Fouce, Rafael
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073714/
https://ncbi.nlm.nih.gov/pubmed/21129369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2010.11.006
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