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The first total synthesis of the (±)-17-methyl-trans-4,5-methyleneoctadecanoic acid and related analogs with antileishmanial activity
The first total synthesis of the marine cyclopropane fatty acid (±)-17-methyltrans- 4,5-methyleneoctadecanoic acid was accomplished in 8 steps and in 9.1% overall yield starting from 1-bromo-12-methyltridecane. The cis analog (±)-17- methyl-cis-4,5-methyleneoctadecanoic acid was also synthesized but...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014621/ https://ncbi.nlm.nih.gov/pubmed/21218160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.09.083 |
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