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First total synthesis and antiprotozoal activity of (Z)-17-methyl-13-octadecenoic acid, a new marine fatty acid from the sponge Polymastia penicillus

The first total synthesis for the (Z)-17-methyl-13-octadecenoic acid was accomplished in seven steps and in a 45% overall yield. The use of (trimethylsilyl)acetylene was key in the synthesis. Based on a previous developed strategy in our laboratory the best synthetic route towards the title compound...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Carballeira, Néstor M., Montano, Nashbly, Balaña-Fouce, Rafael, Prada, Christopher Fernández
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743988/
https://ncbi.nlm.nih.gov/pubmed/19527698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2009.06.140
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