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Targeting of AID-mediated sequence diversification to immunoglobulin genes
Activation-induced cytidine deaminase (AID) is a key enzyme for antibody-mediated immune responses. Antibodies are encoded by the immunoglobulin genes and AID acts as a transcription-dependent DNA mutator on these genes to improve antibody affinity and effector functions. An emerging theme in field...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073656/ https://ncbi.nlm.nih.gov/pubmed/21295456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.12.009 |
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