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Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences
It is thought that gene conversion (GCV) and somatic hypermutation (SHM) of immunoglobulin (Ig) genes occur in two steps: the generation of uracils in DNA by activation-induced cytidine deaminase, followed by their subsequent repair by various DNA repair pathways to generate sequence-diversified pro...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118177/ https://ncbi.nlm.nih.gov/pubmed/17178919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061835 |
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