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Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences

It is thought that gene conversion (GCV) and somatic hypermutation (SHM) of immunoglobulin (Ig) genes occur in two steps: the generation of uracils in DNA by activation-induced cytidine deaminase, followed by their subsequent repair by various DNA repair pathways to generate sequence-diversified pro...

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Detaylı Bibliyografya
Asıl Yazarlar: Yang, Shu Yuan, Fugmann, Sebastian D., Schatz, David G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118177/
https://ncbi.nlm.nih.gov/pubmed/17178919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061835
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