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E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction
The immune system is replenished by self-renewing hematopoietic stem cells (HSCs) that produce multipotent progenitors (MPPs) with little renewal capacity. E-proteins, the widely expressed basic helix-loop-helix transcription factors, contribute to HSC and MPP activity, but their specific functions...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072876/ https://ncbi.nlm.nih.gov/pubmed/21273306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-297689 |
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