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E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction

The immune system is replenished by self-renewing hematopoietic stem cells (HSCs) that produce multipotent progenitors (MPPs) with little renewal capacity. E-proteins, the widely expressed basic helix-loop-helix transcription factors, contribute to HSC and MPP activity, but their specific functions...

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Bibliografische gegevens
Hoofdauteurs: Yang, Qi, Esplin, Brandt, Borghesi, Lisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072876/
https://ncbi.nlm.nih.gov/pubmed/21273306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-297689
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