Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link

Protegrin-1 (PG-1) is an 18 residues long, cysteine-rich β-sheet antimicrobial peptide (AMP). PG-1 induces strong cytotoxic activities on cell membrane and acts as a potent antibiotic agent. Earlier we reported that its cytotoxicity is mediated by its channel-forming ability. In this study, we have...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jang, Hyunbum, Arce, Fernando Teran, Mustata, Mirela, Ramachandran, Srinivasan, Capone, Ricardo, Nussinov, Ruth, Lal, Ratnesh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2011
Gaiak:
Protein
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072611/
https://ncbi.nlm.nih.gov/pubmed/21463591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.01.072
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