Antimicrobial Protegrin-1 Forms Ion Channels: Molecular Dynamic Simulation, Atomic Force Microscopy, and Electrical Conductance Studies

Antimicrobial peptides (AMPs) are an emerging class of antibiotics for controlling health effects of antibiotic-resistant microbial strains. Protegrin-1 (PG-1) is a model antibiotic among β-sheet AMPs. Antibiotic activity of AMPs involves cell membrane damage, yet their membrane interactions, their...

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Detalhes bibliográficos
Main Authors: Capone, Ricardo, Mustata, Mirela, Jang, Hyunbum, Arce, Fernando Teran, Nussinov, Ruth, Lal, Ratnesh
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Protein
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877344/
https://ncbi.nlm.nih.gov/pubmed/20513409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.02.024
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