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The K3 Fragment of Amyloidogenic β(2)-Microglobulin Forms Ion Channels: Implication for Dialysis Related Amyloidosis
β(2)-microglobulin (β(2)m) amyloid deposits are linked to dialysis related amyloidosis (DRA) in hemodialysis patients. The mechanism by which β(2)m causes DRA is not understood. It is also unclear whether only the full-length β(2)m induces pathophysiology or if proteolytic fragments are sufficient f...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782653/ https://ncbi.nlm.nih.gov/pubmed/19824733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9049299 |
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