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Synthesis and proteasome inhibition of lithocholic acid derivatives
A new class of proteasome inhibitors was synthesized using lithocholic acid as a scaffold. Modification at the C-3 position of lithocholic acid with a series of acid acyl groups yielded compounds with a range of potency on proteasome inhibition. Among them, the phenylene diacetic acid hemiester deri...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072167/ https://ncbi.nlm.nih.gov/pubmed/21388808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.02.041 |
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