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The Werner's Syndrome RecQ Helicase/Exonuclease at the Nexus of Cancer and Aging
Werner's Syndrome (WS) or adult-onset progeria is an autosomal recessive disorder of accelerated aging caused by mutations of the DNA RecQ helicase/exonuclease (WRN). WRN is an ATP-dependent helicase with 3′ to 5′ DNA exonuclease activity that regulates the replicative potential of dividing cel...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
University Clinical, Education & Research Associate (UCERA)
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071901/ https://ncbi.nlm.nih.gov/pubmed/21365542 |
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