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Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase

Werner syndrome (WS) is a human autosomal recessive genetic instability and cancer predisposition syndrome with features of premature aging. Several genetically determined mouse models of WS have been generated, however none develops features of premature aging or an elevated risk of neoplasia unles...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dhillon, Kiranjit K., Sidorova, Julia M., Albertson, Tina M., Anderson, Judith B., Ladiges, Warren C., Rabinovitch, Peter S., Preston, Bradley D., Monnat, Raymond J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818259/
https://ncbi.nlm.nih.gov/pubmed/19896421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.09.013
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