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Increased IGF-1 in muscle modulates the phenotype of severe SMA mice
Spinal muscular atrophy (SMA) is an inherited motor neuron disease caused by the mutation of the survival motor neuron 1 (SMN1) gene and deficiency of the SMN protein. Severe SMA mice have abnormal motor function and small, immature myofibers early in development suggesting that SMN protein deficien...
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主要な著者: | , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Oxford University Press
2011
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071675/ https://ncbi.nlm.nih.gov/pubmed/21325354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr067 |
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