Improvement of Neuromuscular Synaptic Phenotypes without Enhanced Survival and Motor Function in Severe Spinal Muscular Atrophy Mice Selectively Rescued in Motor Neurons

In the inherited childhood neuromuscular disease spinal muscular atrophy (SMA), lower motor neuron death and severe muscle weakness result from the reduction of the ubiquitously expressed protein survival of motor neuron (SMN). Although SMA mice recapitulate many features of the human disease, it ha...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Paez-Colasante, Ximena, Seaberg, Bonnie, Martinez, Tara L., Kong, Lingling, Sumner, Charlotte J., Rimer, Mendell
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2013
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781079/
https://ncbi.nlm.nih.gov/pubmed/24086650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075866
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