Impaired Synaptic Vesicle Release and Immaturity of Neuromuscular Junctions in Spinal Muscular Atrophy Mice

The motor neuron disease spinal muscular atrophy (SMA) causes profound muscle weakness that most often leads to early death. At autopsy, SMA is characterized by loss of motor neurons and muscle atrophy, but the initial cellular events that precipitate motor unit dysfunction and loss remain poorly ch...

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Detalhes bibliográficos
Main Authors: Kong, Lingling, Wang, Xueyong, Choe, Dong W., Polley, Michelle, Burnett, Barrington G., Bosch-Marcé, Marta, Griffin, John W., Rich, Mark M., Sumner, Charlotte J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746673/
https://ncbi.nlm.nih.gov/pubmed/19158308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4434-08.2009
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