Impaired Synaptic Vesicle Release and Immaturity of Neuromuscular Junctions in Spinal Muscular Atrophy Mice

The motor neuron disease spinal muscular atrophy (SMA) causes profound muscle weakness that most often leads to early death. At autopsy, SMA is characterized by loss of motor neurons and muscle atrophy, but the initial cellular events that precipitate motor unit dysfunction and loss remain poorly ch...

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Autori principali: Kong, Lingling, Wang, Xueyong, Choe, Dong W., Polley, Michelle, Burnett, Barrington G., Bosch-Marcé, Marta, Griffin, John W., Rich, Mark M., Sumner, Charlotte J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746673/
https://ncbi.nlm.nih.gov/pubmed/19158308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4434-08.2009
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