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The Comparative Immunogenicity of Human and Porcine Factor VIII in Hemophilia A Mice

Inhibitory antibodies to factor VIII (fVIII inhibitors) are the most significant complication in the management of hemophilia A. The immunogenicity of fVIII may be driven in part by structural determinants within the fVIII molecule itself. Regions of non-identity between human and porcine fVIII poss...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Healey, J. F., Parker, E. T., Barrow, R. T., Langley, T. J., Church, W. R., Lollar, P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071503/
https://ncbi.nlm.nih.gov/pubmed/19572065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH08-12-0818
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