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The Comparative Immunogenicity of Human and Porcine Factor VIII in Hemophilia A Mice
Inhibitory antibodies to factor VIII (fVIII inhibitors) are the most significant complication in the management of hemophilia A. The immunogenicity of fVIII may be driven in part by structural determinants within the fVIII molecule itself. Regions of non-identity between human and porcine fVIII poss...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071503/ https://ncbi.nlm.nih.gov/pubmed/19572065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH08-12-0818 |
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