A Novel Intermediate in the Reaction of Seleno CYP119 with m-Chloroperbenzoic Acid

Cytochrome P450 mediated monooxygenation generally proceeds via a reactive ferryl intermediate coupled to a ligand radical [Fe(IV)=O](+.) referred to as Compound I (Cpd I). The proximal cysteine thiolate ligand is a critical determinant of the spectral and catalytic properties of P450 enzymes. To ex...

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Detaylı Bibliyografya
Asıl Yazarlar: Sivaramakrishnan, Santhosh, Ouellet, Hugues, Du, Jing, McLean, Kirsty J., Medzihradszky, Katalin F., Dawson, John H., Munro, Andrew W., Ortiz de Montellano, Paul R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071435/
https://ncbi.nlm.nih.gov/pubmed/21381758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101728y
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