Interaction of Mycobacterium tuberculosis CYP130 with Heterocyclic Arylamines

The Mycobacterium tuberculosis P450 enzymes are of interest for their pharmacological development potential, as evidenced by their susceptibility to inhibition by antifungal azole drugs that normally target sterol 14α-demethylase (CYP51). Although antifungal azoles show promise, direct screening of...

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Autori principali: Podust, Larissa M., Ouellet, Hugues, von Kries, Jens P., Ortiz de Montellano, Paul R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
Soggetti:
Protein Structure and Folding
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757224/
https://ncbi.nlm.nih.gov/pubmed/19605350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017632
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