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Interaction of Mycobacterium tuberculosis CYP130 with Heterocyclic Arylamines

The Mycobacterium tuberculosis P450 enzymes are of interest for their pharmacological development potential, as evidenced by their susceptibility to inhibition by antifungal azole drugs that normally target sterol 14α-demethylase (CYP51). Although antifungal azoles show promise, direct screening of...

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Autores principales: Podust, Larissa M., Ouellet, Hugues, von Kries, Jens P., Ortiz de Montellano, Paul R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2757224/
https://ncbi.nlm.nih.gov/pubmed/19605350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017632
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