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Biochemical and structural characterization of CYP124: A methyl-branched lipid ω-hydroxylase from Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) produces a variety of methyl-branched lipids that serve important functions, including modulating the immune response during pathogenesis and contributing to a robust cell wall that is impermeable to many chemical agents. Here, we report characterization of Mtb CYP12...

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Библиографические подробности
Главные авторы: Johnston, Jonathan B., Kells, Petrea M., Podust, Larissa M., Ortiz de Montellano, Paul R.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791619/
https://ncbi.nlm.nih.gov/pubmed/19933331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907398106
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