MYCOBACTERIUM TUBERCULOSIS CYP130: CRYSTAL STRUCTURE, BIOPHYSICAL CHARACTERIZATION, AND INTERACTIONS WITH ANTIFUNGAL AZOLE DRUGS

CYP130 is one of the 20 Mycobacterium tuberculosis cytochrome P450 enzymes, only two of which, CYP51 and CYP121, have so far been studied as individually expressed proteins. Herein we characterize a third heterologously expressed Mycobacterium tuberculosis cytochrome P450, CYP130, by UV-visible spec...

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Bibliographic Details
Main Authors: Ouellet, Hugues, Podust, Larissa M., Ortiz de Montellano, Paul R.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958778/
https://ncbi.nlm.nih.gov/pubmed/18089574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708734200
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