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The regulatory subunits of PI3K, p85α and p85β, interact with XBP-1 and increase its nuclear translocation
Despite the fact that X-box binding protein-1 (XBP-1) is one of the main regulators of the unfolded protein response (UPR), the modulators of XBP-1 are poorly understood. Here, we show that the regulatory subunits of phosphotidyl inositol 3-kinase (PI3K), p85α (encoded by Pik3r1) and p85β (encoded b...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071012/ https://ncbi.nlm.nih.gov/pubmed/20348926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2099 |
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