RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci

In response to DNA double-strand breaks (DSBs), BRCA1 forms biochemically distinct complexes with certain other DNA damage response proteins. These structures, some of which are required for homologous recombination (HR)-type DSB repair, concentrate at distinct nuclear foci that demarcate sites of g...

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Autors principals: Hu, Yiduo, Scully, Ralph, Sobhian, Bijan, Xie, Anyong, Shestakova, Elena, Livingston, David M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070932/
https://ncbi.nlm.nih.gov/pubmed/21406551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2011011
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