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Increased Expression of P-Glycoprotein Is Associated with Doxorubicin Chemoresistance in the Metastatic 4T1 Breast Cancer Model

Development of drug resistance is one of the major causes of breast cancer treatment failure. The goal of this study was to understand the chemoresistance mechanism using the highly metastatic 4T1 breast cancer model, which emulates stage IV breast cancer in humans. The metastatic 4T1 breast cancer...

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Bibliografische gegevens
Hoofdauteurs: Bao, Lili, Haque, Aliyya, Jackson, Kamilah, Hazari, Sidhartha, Moroz, Krzysztof, Jetly, Rachna, Dash, Srikanta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069823/
https://ncbi.nlm.nih.gov/pubmed/21281816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.029
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